… separation on the pancreatic oxidative and inflammatory damages along with metabolic impairment in response to chronic social defeat stress in young adult male rats

F Eskandari, M Salimi, F Khodagholi… - Journal of Diabetes & …, 2021 - Springer
… trunk blood for assessment of fasting plasma corticosterone, … stress also elevates the
proinflammatory cytokines levels [16]… variable in response to chronic stress, with a decrease or …

[HTML][HTML] Sex differences underlying pancreatic islet biology and its dysfunction

M Gannon, RN Kulkarni, MT Hubert… - Molecular metabolism, 2018 - Elsevier
… and despite similar plasma glucose levels, healthy women exhibit … Islets from elderly female
rats showed elevated … -inflammatory cytokines including IL-6 from stimulated macrophages. …

Pathways linking the early environment to long-term health and lifespan

SK Barnes, SE Ozanne - Progress in biophysics and molecular biology, 2011 - Elsevier
… , such as the endocrine pancreas. This was consistent with … studies in rodents showing that
when pregnant rats were fed … rate, body temperature, plasma glucose, changes in IGF-1 and …

[HTML][HTML] High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring

T de Castro Barbosa, LR Ingerslev, PS Alm… - Molecular …, 2016 - Elsevier
… -secreting cells in whole pancreas from 5-day-old female rats (E) … plasma insulin levels in
F1 female rats (Figure 2B), while F2-… biogenesis is differently regulated between generations. …

Intrauterine programming of the endocrine pancreas

C Remacle, O Dumortier, V Bol… - Diabetes, Obesity …, 2007 - Wiley Online Library
during pregnancy clearly exhibited lower plasma insulin … of β cells to cytotoxic cytokines and
to oxidative stress. Cellular and … diet during pregnancy on the fetal rat endocrine pancreas. …

Mechanisms in endocrinology: nutrition as a mediator of oxidative stress in metabolic and reproductive disorders in women

E Diamanti-Kandarakis, O Papalou… - European journal of …, 2017 - academic.oup.com
… -rich meals on postprandial plasma inflammatory cytokines or a … in diabetic patients has
detrimental effects in pancreatic cell … Specifically, female high-AGE-fed rats displayed increased …

[HTML][HTML] Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress

ER Christoforou, AN Sferruzzi-Perri - Cellular and Molecular Life Sciences, 2020 - Springer
… tissue is present from birth in humans, but not rodents, even … is a main cause of fetal growth
retardation in women living at … metabolic organs, namely the pancreas, liver, skeletal muscle …

Plastics derived endocrine‐disrupting compounds and their effects on early development

S Basak, MK Das, AK Duttaroy - Birth defects research, 2020 - Wiley Online Library
… of PPARγ in rat placenta and changes in the expression of its downstream … after the exposure,
showing decreased pancreatic ß-cell function and mass, reduced insulin levels in plasma

Epigenetic modifications in pancreas development, diabetes, and therapeutics

S Kaimala, CA Kumar, MZ Allouh… - Medicinal Research …, 2022 - Wiley Online Library
levels of SIRT5 in serum. Further investigations using pancreatic cell lines, MIN6 (mouse)
and INS-1 (rat), … CD8 T cells into the pancreas in response to the cytokines secreted by T cells …

Obesity-initiated metabolic syndrome and the kidney: a recipe for chronic kidney disease?

SP Bagby - Journal of the American Society of Nephrology, 2004 - journals.lww.com
… latter raises plasma glucose content and stimulates pancreatic insulin release, … cytokines
(Figure 1). Abdominal fat is unique in … -fed female rats transmit this phenotype to their progeny ( …